You can get from Arequipa to Cusco by bus, flight, private transfer, or rental car.
After extensively exploring Peru, from Arequipa’s colonial charm to Cusco’s high-altitude magic, I’ve experienced firsthand what it takes to navigate the country’s long-distance routes.
Whether looking for the most affordable option or the fastest way to travel, this guide breaks down all the best ways to get from Arequipa to Cusco by bus, flight, private transfer, or rental car.
To ensure accuracy, I also consulted Jean Nájera, CEO of Guatego and an expert in Latin American transportation logistics, to verify the most current routes, timing, and travel advice.
Together, we’ve compiled a clear, up-to-date overview that helps you make the best decision based on your time, comfort, and budget.
Quick Info:
I’ve traveled this route more than once. Trust me, the bus is the best value if you’ve got time. It’s the cheapest way (USD 27, about 10–13 hours) and the most popular. If you’re short on time or comfort is your priority, hop on a flight. It’s only about 1 hour and gives you a stunning bird’ s-eye view of the Andes!
Transportation Options
The following table outlines all transportation options:
| Method | Time | Price |
|---|---|---|
| Bus | 10-13 hrs | $27 to 47 |
| Flight | ~1 hr | – |
| Private Transfer | ~10 hrs | – |
| Rental Car | ~9.5 hrs | – |
1. Bus
Journey Duration: 10-11 hours
This is one of the most breathtaking bus rides in Peru, and the journey lasts about 10-13 hours.
The buses are modern and well-equipped, air-conditioned, and have onboard bathrooms and televisions.
Additionally, there are free blankets, charging stations, and a selection of snacks and beverages. You can also try to fall asleep on comfortable, reclining seats that are incredibly convenient for these night buses!
All the trips are at night, so you don’t have to spend your time traveling during the day.
These long-distance bus trips are also usually the cheapest transportation option. So, depending on your chosen company, the prices range from USD 27 to USD 47.
Two tourist bus companies operate this route: Cruz del Sur and Transzela. You can choose different types of busses for your journey: VIP Bus, 140 Reclining Seats Bus, and 160 Reclining Seats Bus.
140 Reclining Seats Bus Schedule:
The table below displays the bus timetable, detailing departure times, journey lengths, and fares.
| Departure | Arrival | Duration | Price | |
|---|---|---|---|---|
| 06:05pm | 07:40am | 13h 35m | $38 |  |
| 07:00pm | 05:00am | 10h | $27 | |
| 07:00pm | 09:00am | 14h | $38 | |
| 08:30pm | 09:45am | 13h 15m | $38 | |
| 09:20pm | 10:45am | 13h 25m | $38 | |
| 11:45pm | 12:50pm | 13h 5m | $38 | |
| 11:45pm | 11:55am | 12h 10m | $38 | |
160 Reclining Seats Bus Schedule:
The table below displays the bus timetable, detailing departure times, journey lengths, and fares.
| Departure | Arrival | Duration | Price | |
|---|---|---|---|---|
| 07:30pm | 08:40am | 13h 10m | $47 | |
| 08:00pm | 06:40am | 10h 40m | $36 | |
| 09:00pm | 07:40am | 10h 40m | $35 | |
| 11:45pm | 12:50pm | 13h 5m | $47 | |
| 11:55pm | 11:55am | 12h | $47 | |
VIP Bus Schedule:
The table below displays the bus timetable, detailing departure times, journey lengths, and fares.
2. Flight
Journey Duration: ~1 hour
If you want a quick trip from Arequipa to Cusco, we recommend you get on a flight!
Traveling by plane will get you from Arequipa to Cusco in no time! While it’s often the most expensive option, the trip is definitely worth it!
The air distance between Arequipa and Cusco is 324 kilometers or 201 miles. You will arrive in Cusco in about 1 hour and experience some of the most scenic views of the Andean plateau below!
Multiple airlines are providing reliable services directly between Arequipa and Cusco.
The prices of plane tickets vary depending on the season, so it’s best to check for flights in advance and get your tickets!
3. Private Transfer
Journey Duration: ~10 hour
A private transfer is another good option if you want comfort and ease on this long trip from Arequipa to Cusco, especially if you’re traveling in a group!
Several tourist agencies provide these services with various comfortable vehicles!
You can choose between a regular car and larger vehicles, such as minivans, that can accommodate even larger groups!
Because a private transfer is available anytime, you can plan your itinerary and arrive in Cusco whenever you want.
Even though a private transfer is more expensive than other options, it will make getting to Cusco and this 10-hour journey easier and more comfortable!
4. Rental Car
Journey Duration: 9 hours 20 minutes
Renting a car allows you to travel at your own pace and is much faster than public transportation.
The car trip takes about 9 hours, depending on how many stops you make.
Furthermore, car rentals in Arequipa are very affordable, so this option is well worth considering!
You must provide all the necessary documents to your car rental agency and prepare for a long road trip!
What I’d Personally Recommend:
If you’re traveling overnight and want to save on accommodation, the 140° reclining seat bus is surprisingly comfy. I’ve even managed decent sleep on it!
But if you’re flying in after a trek or planning a tight itinerary, the 1-hour flight is an absolute game-changer.
Best day tours in Cusco, Peru
Get Your Guide helps you find the best tours wherever you are heading. It’s usually the first website I check when I plan a trip to a new place.
Frequently Asked Questions
Is there a train?
There is currently no direct train operating.
Is there a direct bus?
Yes, direct bus services depart from Terminal Terrestre de Arequipa and Terrapuerto de Arequipa and arrive in Cusco. You can choose from a few buses: VIP Bus, Tourist Bus, 140 Reclining Seat Bus, 160 Reclining Seat Bus, and 180 Reclining Seat Bus.
Is the road scenic?
Absolutely! I’ve done the bus ride a few times, and the changing views from desert to high Andean peaks are incredible.
What’s the traffic like leaving Arequipa?
Mornings can be busy, so if you’re driving or taking a transfer, try to head out before 8 AM to avoid delays.
Want to pass this along? You can credit this resource:
Universal Traveller – How to Get from Arequipa to Cusco
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