4 Best Ways to get from Cartagena to Medellín, Colombia

AnaMarija Mishachkovska 26 Jun 2023 Last updated: 5 Apr 2025 4 min read No comments


You can get from Cartagena to Medellín by bus, private transfer, flight, or rental car.

The cheapest option is by bus, which costs USD 70 and takes between 13.5 and 14.5 hours.

The most popular option is the flight, being the quickest and most convenient alternative.

The fastest way is also by flight, which takes just over one hour!

I’ve experienced the rhythm of Colombia’s cities and the tranquility of its remote areas, all through its diverse transport system.

This article will give you a firsthand look at navigating this beautiful country and getting from Cartagena to Medellín without any hassle!

Getting to Medellín from Cartagena

MethodTimePrice
Bus13.5-14.5 hrs$70 to 79
Private Transfer12-13 hrs$121 to 390
Flight~1 hr+$80
Rental Car12-13 hrs

1. Bus

Journey Duration: 13.5-14.5 hours

Taking a coach bus or luxury bus is a popular and economical option for traveling from Cartagena to Medellín.

The journey takes approximately 13.5-14 hours, and buses usually run multiple times a day, with departures ranging from early morning to late at night. 

Companies such as Expreso Brasilia and Rapido Ochoa are prominent operators on this route. A ticket for a regular coach bus typically costs between USD 70  to USD 79, while a luxury bus ticket ranges from USD 71 to USD 79.

The buses have reclining seats, air conditioning, Wi-Fi, and onboard restrooms, offering a more comfortable journey. 

By taking a bus from Cartagena to Medellín, you not only save on travel expenses but also have the opportunity to take in the diverse landscapes of Colombia through the window, making it an experience in itself!

There are several departures day and night, so we recommend checking out the schedules and booking your tickets online in advance!

Coach Bus Schedule

The table below displays the coach bus timetable, detailing departure times, journey lengths, and fares.

DEPETADURPX
11:00am12:30am13h 30m$70
04:30pm05:30am13h$70
06:30pm07:30am13h$70
08:30pm09:30am13h$70
07:30pm09:00am13h 30m$79

Luxury Bus Schedule

DEPETADURPX
07:00am09:15pm14h 15m$71
01:00pm02:30am13h 30m$71
03:45pm06:00am14h 15m$71
05:30pm07:00am13h 30m$71
07:30pm09:00am13h 30m$71
09:30pm11:00am13h 30m$71
07:00am09:15pm14h 15m$79
01:00pm02:30am13h 30m$79
03:45pm06:00am14h 15m$79
05:30pm07:00am13h 30m$79
09:30pm11:00am13h 30m$79

2. Private Transfer

Journey Duration: Custom Time

With this option, you can hire a vehicle with a driver for the approximately 640-kilometer journey, which generally takes around 12 hours.

Several companies offer private transfer services, such as Transglobal Ejecutivos and Transportes Especiales Aliados.

The cost of a private transfer typically starts from USD 116 and can go up depending on the type of vehicle, number of passengers, and any additional services required.

Most companies provide a choice between standard cars, SUVs, and vans, allowing you to select a vehicle that best suits the size of your group and your preferences.

You can schedule the pickup time based on your convenience and be free to make stops along the way.

Prices for a private transfer

  • Up to 3 passengers (Standard Car): USD 121
  • Up to 2 passengers (SUV Car): USD 390

3. Flight

Journey Duration: 1 hour 15 minutes

The flight duration is approximately 1 hour and 15 minutes, and airlines such as Avianca and LATAM operate multiple daily flights between the two cities.

Prices for one-way tickets generally start from around USD 80, depending on the time of booking and the airline.

Flights from Cartagena depart from Rafael Núñez International Airport (CTG), about 5 kilometers from the city center.

You can reach the airport by taxi, a common mode of transportation in Cartagena, or through ride-sharing apps.

Upon arrival in Medellín, you will land at José María Córdova International Airport (MDE), which is situated approximately 35 kilometers southeast of the city center. 

When booking flights, it’s advisable to do so well in advance to secure the best prices!

Additionally, be aware that budget airlines often have additional fees for checked luggage and in-flight services, so consider this when comparing prices.

In summary, flying from Cartagena to Medellín offers a swift and convenient alternative to road travel, allowing you to maximize your time exploring the diverse offerings of Medellín.

4. Rental Car

Journey Duration: 12-13 hours

The distance between the two cities is approximately 640 kilometers (around 400 miles), and the drive can take anywhere from 12 to 13 hours, depending on traffic and the route taken.

Rental prices can range from USD 40 to USD 100 per day, depending on your car type. It’s essential to book in advance, especially during peak seasons!

The primary route from Cartagena to Medellín is via Ruta del Sol (Route 90 and Route 25), and it’s recommended to use a GPS for accurate directions.

Keep in mind that this journey involves toll roads, so have some cash handy for the toll fees.

As the journey is long, plan for rest stops and be cautious about where you stop, especially at night. We suggest starting early in the morning to avoid night driving and taking breaks in well-populated areas.

Lastly, be aware of the local driving habits and road conditions. Drive defensively and stay within speed limits.

Renting a car to travel from Cartagena to Medellín is ideal for those who value autonomy and the ability to explore off-the-beaten-path destinations along the way.

Best day tours in Medellín

Get Your Guide helps you find the best tours wherever you are heading. It’s usually the first website I check when I plan a trip to a new place.

Frequently Asked Questions

Are there direct flights?

Yes, several airlines, including Avianca and LATAM, offer direct flights.

How long is the flight?

The flight takes approximately 1 hour and 15 minutes.

What are the main bus companies operating this route?

The main bus companies are Expreso Brasilia and Rapido Ochoa.

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